What medication is commonly used for rectal inflammation and discomfort?

Hydrocortisone suppositories are commonly used to treat rectal inflammation and discomfort because hydrocortisone is a steroid that reduces inflammation and relieves symptoms such as pain, itchiness, and swelling. By delivering the medication directly to the affected area in suppository form, it provides localized relief for conditions such as hemorrhoids, anal fissures, and proctitis, where inflammation occurs.

Other medications listed, like aspirin, ibuprofen, and acetaminophen, primarily serve as systemic analgesics or anti-inflammatory agents. While they can reduce pain and inflammation throughout the body, they are not specifically designed for localized rectal symptoms. Therefore, hydrocortisone suppositories are preferred in this case due to their targeted action and effectiveness in managing rectal issues.