Which condition is characterized by ulcers in the stomach or duodenum?

Peptic Ulcer Disease is characterized by the presence of ulcers in the stomach (gastric ulcers) or the duodenum (duodenal ulcers). This condition arises when the protective mucosal lining of the gastrointestinal tract is compromised, leading to the erosion of the underlying tissue. Several factors contribute to the development of these ulcers, including infection with Helicobacter pylori, excessive use of nonsteroidal anti-inflammatory drugs (NSAIDs), and an increase in gastric acid production.

In contrast to this condition, gastritis involves inflammation of the stomach lining but does not specifically refer to ulceration. Diverticulitis is associated with inflammation of diverticula in the colon, and gastroesophageal reflux disease (GERD) pertains to the retrograde flow of stomach contents into the esophagus. Therefore, peptic ulcer disease is the most accurate description of ulcers occurring in the stomach or duodenum.