Which physiological process may decrease during aortic regurgitation?

During aortic regurgitation, there is a backflow of blood from the aorta into the left ventricle during diastole. This can lead to decreased forward flow of blood into the systemic circulation, particularly during times of exertion when the heart is challenged to meet the body's increased demand for oxygen and nutrients.

As the left ventricle accommodates the increased volume due to the regurgitant flow, it may become dilated and less effective at contracting, which can ultimately decrease cardiac output—especially during physical activity. When the heart's output is compromised, this can lead to inadequate blood supply to various organs and tissues during exertion, which can manifest as fatigue or other symptoms.

This relationship is crucial for understanding how aortic regurgitation affects the intricate balance of blood flow, particularly when the body increases its demand for oxygenated blood during exercise.